Rodent Ocular Disease Models

As a global leader in preclinical ophthalmic research, Creative Biolabs offers numerous rodent ocular diseases models for worldwide clients to enable directed and meaningful preclinical drug discovery and development programs. By leveraging the wealth of information that we have on each ocular disease model, our experienced specialists can help you choose appropriate models and assays. In addition, we can also provide customized studies to meet the specific needs of a particular compound or discovery program.

Our Advantage

At Creative Biolabs, we understand that innovative ocular disease model development is essential for your drug's success. With meticulous research and objective interpretation of data, our experienced Ph.D. and M.D. study directors perform standard guidelines and work closely with Creative Biolabs' other preclinical development multidisciplinary teams to advance your compound and device innovations. In particular, we have developed an advanced ophthalmic platform to help us ensure your project a success which consists of a series of professional equipments, such as electroretinography (ERG), tonometry (IOP), optical coherence tomography (OCT), pachymetry, digital fundus photography, vitrectomy and quantitative autoradiography.

Fig.1 From gene discovery to therapy of retinal
degenerative diseases. (Veleri S, 2015) Ocular Models Available at Creative Biolabs

Creative Biolabs can provide numerous rodent research models to enable directed and meaningful preclinical drug discovery and development programs. With extensive experience, we conduct each model coupled with different parameters that can be used to evaluate the efficacy of candidate drugs. Importantly, our professional team which is supported by internal PK/Bioanalytical, ex vivo pharmacology and in vitro biology experts will work closely with you to ensure the most reliable data can be achieved. Learn more details about different ocular disease models:

• Corneal Neovascularization Model
• Choroidal Neovascularization Model
• LPS-induced Uveitis Model
• Model of Retinal Degeneration & Neuroprotection
• Normotensive & Hypertensive Intraocular Pressure Model
• Allergic Conjunctivitis Model
• Dry Eye Model
• Corneal Wound Healing Model
• Diabetic Macular Edema Model
• Infectious Keratitis Model

Creative Biolabs is happy to share our top-notch technology and abundant experience with global customers. Before the initial start of model creation, we will conduct stringent pre-screening ophthalmic exams to eliminate pre-existing ocular defects which could adversely affect the outcome of your ocular studies. If you are interested in the service we can provide, please feel free to contact us or send us an inquiry.

Reference

1. Veleri S, et al. Biology and therapy of inherited retinal degenerative disease: insights from mouse models. Disease models & mechanisms, 2015, 8(2): 109-129.

For Research Use Only.