Home > Products > IL17 & TNF > Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Fab-IgG)

Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Fab-IgG)  (FABIG-175)

Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Fab-IgG) is designed to be expressed as three chains, assembling in vivo and resulting in the construct of Fab-IgG (Tandem Fab-Fc). Fab-IgG has standard Fab and Fc domains, with no mutations, which may permit it has similar affinity binding and PK profile comparable to the parental antibodies. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Rheumatoid arthritis (RA); Plaque psoriasis therapy.

Specifications

Targets
IL17 & TNF
Type
Fab-IgG
Species Reactivity
Human
Target 1
IL17
Host Animal 1
Mouse
Target 2
TNF
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Rheumatoid arthritis (RA); Plaque psoriasis

Targets

Target 1
IL17
Gene ID
UniProt ID
Alternative Names
IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Target 2
TNF
Gene ID
UniProt ID
Alternative Names
TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNFα; cachectin; APC1 protein; TNF, monocyte-derived; TNF-α; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2

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Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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