Home > Products > IL17 & TNF > Recombinant Human Anti-IL17 x Anti-TNF Bispecific Antibody (Single-chain Diabody)

Recombinant Human Anti-IL17 x Anti-TNF Bispecific Antibody (Single-chain Diabody)  (SCDB-H339)

Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (Single-chain Diabody) is designed to be expressed as one polypeptide chain with four variable domains from two parental antibodies. The middle linker is long enough to form scFv dimers between the two diabody chains. This BsAb can block two proinflammatory cytokines simultaneously. It is designed for the research of Rheumatoid arthritis (RA); Plaque psoriasis therapy.

Specifications

Targets
IL17 & TNF
Type
Single-chain Diabody
Species Reactivity
Human
Target 1
IL17
Host Animal 1
Human
Target 2
TNF
Host Animal 2
Human
Application
FuncS; Promising therapeutic agent
Related Disease
Rheumatoid arthritis (RA); Plaque psoriasis

Targets

Target 1
IL17
Gene ID
UniProt ID
Alternative Names
IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Target 2
TNF
Gene ID
UniProt ID
Alternative Names
TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNFα; cachectin; APC1 protein; TNF, monocyte-derived; TNF-α; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2

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