Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (scFv-IgG) (BSSG-H340)

Recombinant Anti-IL17 x Anti-TNF Bispecific Antibody (scFv-IgG) is formed by an IgG and two scFv fragments. The scFvs from an anti-IL17 antibody variable domain are respectively connected to the N terminus of the anti-TNF IgG heavy chains or light chains to form scFv-(H)IgG or scFv-(L)IgG. It is a type of appended IgGs and has 2+2 antigen-binding valency. This BsAb can block two proinﬂammatory cytokines simultaneously. It is designed for the research of Rheumatoid arthritis (RA); Plaque psoriasis therapy.

Datasheet INQUIRY

Specifications

Targets

IL17 & TNF

Type

Appended IgGs

Species Reactivity

Human

Application

FuncS; Promising therapeutic agent

Related Disease

Rheumatoid arthritis (RA); Plaque psoriasis

Targets

Target 1

IL17

Gene ID

3605

UniProt ID

Q16552

Alternative Names

IL17A; interleukin 17A; IL17; CTLA8; IL-17; IL-17A; interleukin-17A; CTLA-8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)

Target 2

TNF

Gene ID

7124

UniProt ID

P01375

Alternative Names

TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNFα; cachectin; APC1 protein; TNF, monocyte-derived; TNF-α; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

Online Inquiry

Customer Reviews and Q&As

There are currently no customer reviews or questions for Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (scFv-IgG) (BSSG-H340). Click the button below to contact us or submit your feedback about this product.

Recombinant Human Anti-IL17 x Human Anti-TNF Bispecific Antibody (scFv-IgG) (CAT#: BSSG-H340)

Specifications

Targets

Customer Reviews and Q&As