B16F10 In Vitro Micro-carrier Beads Assay (Angiogenesis)
CAT#: ITS-1022-YF55
Target Cell Organism: Mouse
Target Cell Alternative Name: B16-F10
Target Cell Name: B16F10
Assay Type: Angiogenesis Monitoring Assays
Assay Overview
This assay is to provide B16F10-based In Vitro Micro-carrier Beads Assay (Angiogenesis) to accelerate our client's oncology projects. The assay will be customized according to the specific requirements. Please contact our scientists to discuss more details.
Target Cell Name
B16F10
Target Cell Organism
Mouse
Target Cell Background
B16F10 cell line (from Mus musculus C57BL/6J strain) is a convenient and widely used experimental model of highly metastatic melanoma to study cytotoxicity, migration, metastatic spread and tissue invasion. B16-F10 is a cell line exhibiting a morphology of spindle-shaped and epithelial-like cells that was isolated from skin tissue of a mouse with melanoma. Use these cells in your skin cancer research.
Target Cell Alternative Name
B16-F10
Related Diseases
Melanoma
Research Area
Oncology
Assay Name
In Vitro Micro-carrier Beads Assay (Angiogenesis)
Short Description
B16F10-cell based In Vitro Micro-carrier Beads Assay (Angiogenesis)
Assay Description
Migration of cells from cell-coated micro-carrier beads to the surface of cell culture wells or dishes is measured in this assay. Cells are grown on the surface of carrieer beads and beads are then placed in a plate well or dish over particular incubation periods.
Assay Type
Angiogenesis Monitoring Assays
Assay Type Details
Local and regional metastasis is a life-threatening condition in cancer, which is hard to control with the available cancer treatment options. In metastasis, cancer cells move away from primary tumors and travel through the blood and lymphatic system and form new tumors on other parts. A vascular network growth is important for cancer metastasis. Angiogenesis is a process that is known as the formation of new blood vessels with the help of existing blood vessels and angiogenesis has been reported to play a major role in cancer growth and metastasis. Tumors can send chemical signals to nearby normal tissues to stimulate angiogenesis. New blood vessels can feed growing tumors with nutrients and oxygen, allowing cancer cells to spread (metastasis).