Preclinical Testing Services
Creative Biolabs offers integrated scientific support for your compound's journey from early discovery to later-stage development. We provide advanced in vivo and in vitro modeling, high-resolution bioanalytical profiling, and comprehensive compound profiling studies. Clients can expect to gain high-fidelity, predictive data, accelerated timelines due to streamlined documentation, and reduced costs by identifying potential adverse effects early in the development process. Our expertise transforms ambiguous research data into clear, actionable scientific strategy.
Introduction of Preclinical Testing Services
The drug discovery and development pathway is a long journey, and complications and inefficiencies at the late stage can create costly delays. Therefore, safety and efficacy profiles of drug candidates before clinical trials are critical stages to avoid unnecessary loss. Preclinical testing in animal models can help to foresee potential risks of drug candidates before exposure to humans, and hence reduce the cost for pharmaceutical industries and help to make the appropriate choice. Now that immunotherapy has emerged as a major approach to treat malignancies, including small chemical molecules and biologic drugs, we are dedicated to serving preclinical testing for immunotherapy potential drugs.
Discover how we can help - Request a consultation.
Fig.1 Recent 3D bioprinted cancer models for preclinical testing. 1
What We Can Offer
Creative Biolabs is dedicated to providing flexible solutions and accelerated timelines for our clients who care about making a difference for immuno-oncology. Our experienced scientists and skillful technicians execute individual studies via state-of-the-art technologies in a global network of facilities. Furthermore, custom preclinical testing studies, which are designed to fit the clients' goals, are also available in Creative Biolabs. Our regulatory experts ensure that all preclinical testing services are in compliance with worldwide standards for quality and regulations to smooth the path to market. Here are provided services for your quick check, but not limited to these.
Efficacy Models
We offer efficacy models, including cell line-derived xenograft models, humanized models, immunodeficient mice, syngeneic models, and chemical-induced cancer models to support different oncology areas that incorporate biomarkers and outcome measures to enable greater success in the clinic.
Antibody and Protein Pharmacology
Our pharmacology program helps clients to accelerate the development of their cancer immunotherapy candidates by investigating the potential actions of compounds or biologics on physiological functions under exposure in the therapeutic range and above.
Antibody and Protein Toxicology
Empowered by our board-certified toxicologists, veterinary surgeons, veterinary pathologists, regulatory specialists, and support technicians, these programs cover a wide range of animal models and employ various routes of administration, and evaluate acute through chronic toxicity and carcinogenicity.
How Creative Biolabs' service Can Assist Your Projects
Why Choose Us
| Our Purposes | Highlight Features |
|---|---|
|
|
Discover how a partnership with us can streamline your research - Get a quote today.
Customer Reviews
-
Faster Report Finalization
The high-quality digital pathology meant we finalized our non-regulated research module weeks ahead of schedule, a crucial benefit for our accelerated decision timeline. - J*n S***h. -
Genetic Signal De-risking
Creative Biolabs facilitated our confidence in a challenging small molecule. Their expertise in mechanistic insight and in vivo follow-up prevented us from prematurely terminating a lead candidate due to a false in vitro positive - a true partnership in translational science. - M*y B***n.
FAQs
Why is Creative Biolabs' approach superior to running standard in vivo models internally?
We offer integrated scientific expertise, specialized model development (like humanized mice and organ-on-a-chip technology), and CLP-compliant infrastructure that are costly to maintain in-house. Our focus is on translational success - we generate not just data, but predictive data that directly informs the design of your first human study.
Our compound is a complex biologic. Can you handle the specialized bioanalytical requirements, such as immune response testing?
Absolutely. We have dedicated bioanalytical strategies for biologics, including validated methods for PK, immune response, and biomarker analysis in complex matrices. Our experience ensures that your biologic is properly characterized for both concentration and potential immune system interaction.
How to Contact Us
Creative Biolabs is committed to end-to-end immuno-oncology preclinical animal testing in compliance with ICH guidelines to meet regulatory requirements. Our experienced team helps clients to avoid roadblocks, anticipate challenges, and expedite preclinical drug development with a wide array of services and expert guidance through this important stage. If you want to have further communication or any other requests, please feel free to contact us.
Related Services
Reference
- van Rijt, Antonia et al. "Preclinical Testing Techniques: Paving the Way for New Oncology Screening Approaches." Cancers vol. 15,18 4466. 7 Sep. 2023. Distributed under an Open Access license CC BY 4.0, without modification. https://doi.org/10.3390/cancers15184466
Download our brochure