Short Description
Quantifies xanthine levels as a marker of purine degradation.
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Xanthine Assay Kit provides high-sensitivity detection of xanthine, a precursor in uric acid formation and a marker of oxidative stress. This assay validates drugs that modulate the purine degradation pathway, offering insights into the mechanisms of gout and tissue ischemia. Its application in biological fluid analysis supports the comprehensive profiling of purine metabolism in pharmaceutical research.
Features
High sensitivity fluorometric option; Validates purine metabolism modulators in hyperuricemia research.
Process Relevance
Oxidative Stress Mechanism Study
Application Stage
Discovery
Applications
Research into hyperuricemia and oxidative stress markers.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 570 nm, Fluorescence Detection (Ex 530 nm / Em 585 nm)
Sample Type
Cell lysate, serum, and other biological samples
Research Areas
Rheumatology; Metabolic Disease
Datasheet