OXPHOSight™ Xanthine Assay Kit

CAT#: ITS-1125-HM50
Product Type: Assay Kit
Species: All Species
Short Description
Quantifies xanthine levels as a marker of purine degradation.
Brand
OXPHOSight
Development Stage
Research-Grade Metabolic Assay Development
Description
The OXPHOSight™ Xanthine Assay Kit provides high-sensitivity detection of xanthine, a precursor in uric acid formation and a marker of oxidative stress. This assay validates drugs that modulate the purine degradation pathway, offering insights into the mechanisms of gout and tissue ischemia. Its application in biological fluid analysis supports the comprehensive profiling of purine metabolism in pharmaceutical research.
Features
High sensitivity fluorometric option; Validates purine metabolism modulators in hyperuricemia research.
Process Relevance
Oxidative Stress Mechanism Study
Application Stage
Discovery
Applications
Research into hyperuricemia and oxidative stress markers.
Qualified With
Internal performance validation using reference standards under defined assay conditions.
Detection Method
Absorbance at 570 nm, Fluorescence Detection (Ex 530 nm / Em 585 nm)
Sample Type
Cell lysate, serum, and other biological samples
Research Areas
Rheumatology; Metabolic Disease
Size
100 tests
Data Output Type
Quantitative (Concentration)
Assay Time
Results in 30 min
LOD
OD 10 µM; FL 3 µM
Species
All Species
Storage
Store at −20 °C upon receipt to maintain reagent stability. Follow recommended handling procedures to ensure consistent assay performance.
Storage Comment
Avoid repeated freeze-thaw cycles. During use, minimize the time components are exposed to room temperature and return them promptly to −20 °C storage after handling. Do not store at elevated temperatures for extended periods.
Expiry Date
6 months under recommended storage conditions to ensure optimal performance.
Note
For bulk pricing or custom reagent inquiries, please contact us by email or phone. Products are shipped on ice via FedEx.
Restrictions
For Research Use Only (RUO). Not intended for diagnostic or therapeutic use.
Shipping
Shipped on ice under temperature-controlled conditions.
Background
Xanthine is a purine base intermediate in the degradation of AMP and GMP to uric acid. It accumulates in rare genetic disorders and can form kidney stones; it is also a substrate for xanthine oxidase.
For Research Use Only | Not For Clinical Use
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