This assay is used for screening and profiling PD-1 (Human) binding molecules (such as anti-PD-1 antibody, ADC) in a cellular context. The assay will be customized according to the client's specific requirements. Please contact our scientists to discuss more details.
Features
Customized to client's specific requirements
Target Cell Name
Jurkat/PD-1 (Human)
Target Cell Organism
Human
Target Cell Background
Creative Biolabs has developed several immune checkpoint stable cell Lines expressing the most popular immune checkpoints to accelerate clients' immunotherapy discovery and clinical translation. Recombinant Jurkat T cell expressing firefly luciferase gene under the control of NFAT response elements with constitutive expression of human PD-1 (Programmed Cell Death 1, PDCD1, SLEB2, CD279, GenBank Accession #NM_005018). Which can be used in binding assays and functional assay.
Target Cell Alternative Name
Jurkat
Related Diseases
Cancer
Research Area
Oncology
Assay Name
In Vitro Cell Binding Assay
Short Description
Screening and profiling for PD-1 (Human) binding molecules (such as anti-PD-1 antibody, ADC) in a cellular context.
Assay Description
Drug candidates screening and profiling assay as a most important analysis for drug discovery. Creative Biolabs provides In Vitro PD-1 (Human) Binding Molecules Screening Assay to screen PD-1 (Human) binding molecules (such as anti-PD-1 antibody, ADC) by cell-based binding FACS analysis. The assay will be customized according to the client's specific requirements. Please contact our scientists to discuss more details.
Assay Alternative Names
Cell-based Binding Assay; Drug Screening and Profiling assay
Assay Type
Cell Binding Assay
Assay Type Details
Screening and profiling PD-1 (Human) binding molecules (such as anti-PD-1 antibody, ADC) by cell-based binding FACS analysis.
Assay MOA
Creative have developed the stable cell line Jurkat/PD-1 (Human), which is designed for screening and profiling PD-1 (Human) binding molecules (such as anti-PD-1 antibody, ADC) by cell-based binding FACS analysis.