Home > Products > CD28 & HN > Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (IgG-Fv)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (IgG-Fv)  (BSGV-H237)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (IgG-Fv) is formed by an Immunoglobulin G (IgG) and a fragment variable Fv region, in which the Fc of IgG is engineered by KIH. The Fv region of an anti-CD28 antibody variable domain is fused to the C terminal of an IgG of anti-HN antibody, or vice versa. The format retains desired characteristics of intact antibodies. This BsAb can retarget T cells to tumor cells. It is designed for the tumor vaccine modification and the research of Tumors therapy.

Specifications
Targets
CD28 & HN
Type
IgG-Fv
Species Reactivity
Human
Target 1
CD28
Host Animal 1
Mouse
Target 2
HN
Host Animal 2
Mouse
Application
FuncS; Promising preventive/therapeutic agent
Related Disease
Tumors
Targets
Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
HN
Gene ID
UniProt ID
Alternative Names
Hemagglutinin-neuraminidase; HN

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