Name: Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (IgG(L)-scFv)
SKU: IGLFV-061
Rating: 5 (1 reviews)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (IgG(L)-scFv) is formed by an IgG and two scFv moieties. The scFv fragments from an anti-CD28 antibody are fused to the C terminus of an anti-HN IgG light (L) chains, or vice versa. It is a type of appended IgGs, which is bispecific and tetravalent (2+2 antigen-binding valency). This BsAb can retarget T cells to tumor cells. It is designed for the tumor vaccine modification and the research of Tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & HN

Type

IgG (L)-scFv

Species Reactivity

Human

Application

FuncS; Promising preventive/therapeutic agent

Related Disease

Tumors

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

Gene ID

912270

UniProt ID

Q9Q2W5

Alternative Names

Hemagglutinin-neuraminidase; HN

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (IgG(L)-scFv) (CAT#: IGLFV-061)

Specifications

Targets

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