Home > Products > CD28 & HN > Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (scFv4-Ig)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (scFv4-Ig)  (FVTIG-061)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (scFv4-Ig) is an appended IgG format, which includes four scFv moieties at the N-termini of the constant regions. It is a bivalent homodimer, in which one anti-CD28 scFv is fused to the CH1 domain of a heavy chain and another anti-HN scFv to the CL domain of a light chain, or vice versa. The resulting leads to 2+2 antigen-binding valency. This BsAb can retarget T cells to tumor cells. It is designed for the tumor vaccine modification and the research of Tumors therapy.

Specifications
Targets
CD28 & HN
Type
Appended IgGs
Species Reactivity
Human
Target 1
CD28
Host Animal 1
Mouse
Target 2
HN
Host Animal 2
Mouse
Application
FuncS; Promising preventive/therapeutic agent
Related Disease
Tumors
Targets
Target 1
CD28
Gene ID
UniProt ID
Alternative Names
CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen
Target 2
HN
Gene ID
UniProt ID
Alternative Names
Hemagglutinin-neuraminidase; HN

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