Name: Recombinant Human Anti-CD28 x Human Anti-HN Bispecific Antibody (scFv-CH3)
SKU: BSFC-H237
Rating: 5 (1 reviews)

Recombinant Anti-CD28 x Anti-HN Bispecific Antibody (scFv-CH3) contains two chains. The anti-CD28 scFv is fused to the Knob-CH3 domain via a hinge region and the same as the anti-HN scFv to the Hole-CH3 domain, or vice versa. The KIH CH3 domains can facilitate to form a heterodimer and this bivalent binding leads to improvement in avidity. This BsAb can retarget T cells to tumor cells. It is designed for the tumor vaccine modification and the research of Tumors therapy.

Datasheet INQUIRY

Specifications

Targets

CD28 & HN

Type

scFv-CH3

Species Reactivity

Human

Application

FuncS; Promising preventive/therapeutic agent

Related Disease

Tumors

Host Animal 1

Mouse

Host Animal 2

Mouse

Targets

Target 1

CD28

Gene ID

940

UniProt ID

P10747

Alternative Names

CD28; CD28 molecule; Cluster of Differentiation 28; Tp44; T-cell-specific surface glycoprotein CD28; CD28 antigen

Target 2

Gene ID

912270

UniProt ID

Q9Q2W5

Alternative Names

Hemagglutinin-neuraminidase; HN

Our products and services are for research use only, and not for use in diagnostic or therapeutic procedures.

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Recombinant Human Anti-CD28 x Human Anti-HN Bispecific Antibody (scFv-CH3) (CAT#: BSFC-H237)

Specifications

Targets

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