Home > Products > CEA & TNFα > Recombinant Anti-CEA VHH x Anti-TNFα VHH BispecificAntibody (Bi-nanobody)

Recombinant Anti-CEA VHH x Anti-TNFα VHH BispecificAntibody (Bi-nanobody)  (BIVHH-041)

Recombinant Anti-CEA x Anti-TNFα Bispecific Antibody (Bi-nanobody) is designed to be expressed as a VHH from anti-CEA antibody variable domains fused with a VHH from an anti-TNFα antibody variable domains. It contains a His-tag at the C/N terminus for affinity purification. The BsAb exits as monomer in reducing and non-reducing conditions. This BsAb can retarget cytokine (TNFα) to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

Specifications
Targets
CEA & TNFα
Type
Bi-nanobody
Species Reactivity
Human
Target 1
CEA
Host Animal 1
llama
Target 2
TNFα
Host Animal 2
llama
Application
FuncS; Promising therapeutic agent
Related Disease
Breast cancer; Ovary cancer; Colon cancer; Lung cancer
Targets
Target 1
CEA
Gene ID
UniProt ID
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
TNFα
Gene ID
UniProt ID
Alternative Names
TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2
Our services and products are only for lab research, not for any diagnostic or therapeutic use.

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