Home > Products > CEA & TNFα > Anti-CEA x Anti-TNFα Bispecific Antibody (IgG-IgG)

Anti-CEA x Anti-TNFα Bispecific Antibody (IgG-IgG)  (BSIG-142)

Anti-CEA x Anti-TNFα Bispecific Antibody (IgG-IgG) is designed to be generated by crosslinking two full length IgGs, anti-CEA and anti-TNFα parental antibodies. A stable linkage is formed between the two antibodies. This BsAb can retarget cytokine (TNFα) to tumor cells. It is designed for the research of Breast cancer; Ovary cancer; Colon cancer; Lung cancer therapy.

Datasheet
Specifications
Targets
CEA & TNFα
Type
IgG-IgG
Species Reactivity
Human
Target 1
CEA
Host Animal 1
Mouse
Target 2
TNFα
Host Animal 2
Mouse
Application
FuncS; Promising therapeutic agent
Related Disease
Breast cancer; Ovary cancer; Colon cancer; Lung cancer
Targets
Target 1
CEA
Gene ID
1048
UniProt ID
A0A024R0K5
Alternative Names
CEACAM5; carcinoembryonic antigen; carcinoembryonic antigen related cell adhesion molecule 5; CEA; CD66e; meconium antigen 100
Target 2
TNFα
Gene ID
7124
UniProt ID
P01375
Alternative Names
TNF; tumor necrosis factor; DIF; TNFA; TNFSF2; TNF-alpha; TNF-a; cachectin; APC1 protein; TNF, monocyte-derived; TNF, macrophage-derived; tumor necrosis factor-alpha; tumor necrosis factor ligand superfamily member 2

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