This is an aptamer development services to screening aptamers binds to the AAAS with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AAAS |
| Alternative Names | Aladin WD Repeat Nucleoporin; Aladin; Achalasia, Adrenocortical Insufficiency, Alacrimia; Allgrove, Triple-A; Adracalin; ADRACALA; Achalasia, Adrenocortical Insufficiency, Alacrimia (Allgrove, Triple-A) ; ADRACALIN; ALADIN; AAASb; GL003; AAAS; AAA |
| Gene ID | 8086 |
| UniProt ID | Q9NRG9 |
| Target Overview | The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |