This is an aptamer development services to screening aptamers binds to the ABCC3 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ABCC3 |
| Alternative Names | ATP Binding Cassette Subfamily C Member 3; Canalicular Multispecific Organic Anion Transporter 2; MOAT-D; CMOAT2; MLP2; MRP3; ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 3; ATP-Binding Cassette Sub-Family C Member 3; Multi-Specific Organic Anion Transporter D; Multidrug Resistance-Associated Protein 3; EST90757; Canicular Multispecific Organic Anion Transporter; Multidrug Resistance Associated Protein; EC 3.6.3.44; EC 6.3.2.4; EC 3.6.3; ABC31; ABCC3 |
| Gene ID | 8714 |
| UniProt ID | O15438 |
| Target Overview | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |