This is an aptamer development services to screening aptamers binds to the ACAT1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ACAT1 |
| Alternative Names | Acetyl-CoA Acetyltransferase 1; Acetyl-CoA Acetyltransferase, Mitochondrial; Acetyl-Coenzyme A Acetyltransferase 1; Acetoacetyl Coenzyme A Thiolase; Acetoacetyl-CoA Thiolase; EC 2.3.1.9; ACAT; THIL; MAT; T2; Mitochondrial Acetoacetyl-CoA Thiolase; Testicular Tissue Protein Li 198; EC 2.3.1; ACAT1 |
| Gene ID | 38 |
| UniProt ID | P24752 |
| Target Overview | This gene encodes a mitochondrially localized enzyme that catalyzes the reversible formation of acetoacetyl-CoA from two molecules of acetyl-CoA. Defects in this gene are associated with 3-ketothiolase deficiency, an inborn error of isoleucine catabolism characterized by urinary excretion of 2-methyl-3-hydroxybutyric acid, 2-methylacetoacetic acid, tiglylglycine, and butanone. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |