This is an aptamer development services to screening aptamers binds to the ACTB with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ACTB |
| Alternative Names | Actin Beta; Actin, Cytoplasmic 1; PS1TP5-Binding Protein 1; Beta Cytoskeletal Actin; I(2)-Acti; Beta-Actin; PS1TP5BP1; Β-Actin; BRWS1; ACTB |
| Gene ID | 60 |
| UniProt ID | P60709 |
| Target Overview | This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |