Anti-ACTN2 Aptamer SELEX Service(Cat#: CTApt-983)
This is an aptamer development services to screening aptamers binds to the ACTN2 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ACTN2 |
| Alternative Names |
Actinin Alpha 2; F-Actin Cross-Linking Protein; Alpha-Actinin-2; Alpha-Actinin Skeletal Muscle Isoform 2; Alpha-Actinin Skeletal Muscle; CMD1AA; MYOCOZ; CMH23; ACTN2; MPD6 |
| Gene ID |
88 |
| UniProt ID |
P35609 |
| Target Overview |
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
