Anti-ACVR1C Aptamer SELEX Service(Cat#: CTApt-994)

This is an aptamer development services to screening aptamers binds to the ACVR1C with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ACVR1C
Alternative Names Activin A Receptor Type 1C; ALK7; Activin Receptor-Like Kinase 7; Activin A Receptor, Type IC; Activin Receptor Type-1C; Activin Receptor Type IC; EC 2.7.11.30; ACVRLK7; ACTR-IC; ALK-7; EC 2.7.11; ACVR1C
Gene ID 130399
UniProt ID Q8NER5
Target Overview ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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