This is an aptamer development services to screening aptamers binds to the ADO with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ADO |
| Alternative Names | 2-Aminoethanethiol Dioxygenase; Cysteamine Dioxygenase; 2-Aminoethanethiol (Cysteamine) Dioxygenase; C10orf22; Cysteamine (2-Aminoethanethiol) Dioxygenase (ADO) ; Chromosome 10 Open Reading Frame 22; EC 1.13.11.19; FLJ14547; ADO |
| Gene ID | 84890 |
| UniProt ID | Q96SZ5 |
| Target Overview | Human thiol dioxygenases include cysteine dioxygenase (CDO; MIM 603943) and cysteamine (2-aminoethanethiol) dioxygenase (ADO; EC 1.13.11.19). CDO adds 2 oxygen atoms to free cysteine, whereas ADO adds 2 oxygen atoms to free cysteamine to form hypotaurine (Dominy et al., 2007 [PubMed 17581819]). |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |