Anti-ADRB2 Aptamer SELEX Service(Cat#: CTApt-1047)
This is an aptamer development services to screening aptamers binds to the ADRB2 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ADRB2 |
| Alternative Names |
Adrenoceptor Beta 2; B2AR; Adrenergic, Beta-2-, Receptor, Surface; Beta-2 Adrenergic Receptor; Beta-2 Adrenoreceptor; Beta-2 Adrenoceptor; ADRB2R; ADRBR; BAR; Adrenoceptor Beta 2, Surface; Adrenoceptor Beta 2 Surface; Catecholamine Receptor; BETA2AR; ADRB2 |
| Gene ID |
154 |
| UniProt ID |
P07550 |
| Target Overview |
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
