This is an aptamer development services to screening aptamers binds to the AFF4 with an affinity of 1nM~1μM.
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
| Target Category | Protein |
| Target | AFF4 |
| Alternative Names | AF4/FMR2 Family Member 4; AF5Q31; MCEF; Major CDK9 Elongation Factor-Associated Protein; ALL1-Fused Gene From Chromosome 5q31 Protein; ALL1 Fused Gene From 5q31; AF4/FMR2 Family, Member 4; Protein AF-5q31; CHOPS; AFF4 |
| Gene ID | 27125 |
| UniProt ID | Q9UHB7 |
| Target Overview | The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |