Anti-AFF4 Aptamer SELEX Service(Cat#: CTApt-1057)

This is an aptamer development services to screening aptamers binds to the AFF4 with an affinity of 1nM~1μM.

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5’ Modification
 
3’ Modification
 
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Certificate of Analysis Lookup

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Lot Number

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Summary

Specifications
Target Category Protein
Target AFF4
Alternative Names AF4/FMR2 Family Member 4; AF5Q31; MCEF; Major CDK9 Elongation Factor-Associated Protein; ALL1-Fused Gene From Chromosome 5q31 Protein; ALL1 Fused Gene From 5q31; AF4/FMR2 Family, Member 4; Protein AF-5q31; CHOPS; AFF4
Gene ID 27125
UniProt ID Q9UHB7
Target Overview The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23).
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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