Anti-AGA Aptamer SELEX Service(Cat#: CTApt-1063)
This is an aptamer development services to screening aptamers binds to the AGA with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
AGA |
| Alternative Names |
Aspartylglucosaminidase; N(4)-(Beta-N-Acetylglucosaminyl)-L-Asparaginase; Glycosylasparaginase; N4-(N-Acetyl-Beta-Glucosaminyl)-L-Asparagine Amidase; EC 3.5.1.26; ASRG; Aspartylglucosylamine Deaspartylase; EC 3.5.1; AGU; AGA; GA |
| Gene ID |
175 |
| UniProt ID |
P20933 |
| Target Overview |
This gene encodes a member of the N-terminal nucleophile (Ntn) hydrolase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta chains that comprise the mature enzyme. This enzyme is involved in the catabolism of N-linked oligosaccharides of glycoproteins. It cleaves asparagine from N-acetylglucosamines as one of the final steps in the lysosomal breakdown of glycoproteins. Mutations in this gene are associated with the lysosomal storage disease aspartylglycosaminuria that results in progressive neurodegeneration. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is subject to proteolytic processing. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
