This is an aptamer development services to screening aptamers binds to the AGXT with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AGXT |
| Alternative Names | Alanine--Glyoxylate And Serine--Pyruvate Aminotransferase; AGT1; AGT; SPT; L-Alanine: Glyoxylate Aminotransferase 1; Alanine-Glyoxylate Aminotransferase; Serine--Pyruvate Aminotransferase; AGXT1; SPAT; PH1; Hepatic Peroxisomal Alanine:Glyoxylate Aminotransferase; Alanine--Glyoxylate Aminotransferase; Serine:Pyruvate Aminotransferase; Primary Hyperoxaluria Type 1; Glycolicaciduria; EC 2.6.1.51; EC 2.6.1.44; Oxalosis I; TLH6; AGXT |
| Gene ID | 189 |
| UniProt ID | P21549 |
| Target Overview | This gene is expressed only in the liver and the encoded protein is localized mostly in the peroxisomes, where it is involved in glyoxylate detoxification. Mutations in this gene, some of which alter subcellular targetting, have been associated with type I primary hyperoxaluria. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |