This is an aptamer development services to screening aptamers binds to the ALAS2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ALAS2 |
| Alternative Names | 5'-Aminolevulinate Synthase 2; 5-Aminolevulinate Synthase, Erythroid-Specific, Mitochondrial; Aminolevulinate, Delta-, Synthase 2; 5-Aminolevulinic Acid Synthase 2; Delta-Aminolevulinate Synthase 2; Delta-ALA Synthase 2; EC 2.3.1.37; ALAS-E; ALASE; ASB; Aminolevulinate, Delta-, Synthase 2 (Sideroblastic/Hypochromic Anemia) ; Sideroblastic/Hypochromic Anemia; Delta-ALA Synthetase; SIDBA1; XLDPP; XLEPP; ALAS2; ANH1; XLSA; |
| Gene ID | 212 |
| UniProt ID | P22557 |
| Target Overview | The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |