This is an aptamer development services to screening aptamers binds to the ALDH7A1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ALDH7A1 |
| Alternative Names | Aldehyde Dehydrogenase 7 Family Member A; Alpha-Aminoadipic Semialdehyde Dehydrogenase; Alpha-AASA Dehydrogenase; P6c Dehydrogenase; Delta1-Piperideine-6-Carboxylate Dehydrogenase; Betaine Aldehyde Dehydrogenase; 26g Turgor Protein Homolog; Antiquitin-1; ATQ1; EPD; PDE; Delta1-Piperideine-6-Carboxylate Dehydrogenease; Aldehyde Dehydrogenase 7 Family, Member A1; Epididymis Secretory Sperm Binding Protein; Aldehyde Dehydrogenase Family 7 Member A1; Antiquitin 1; EC 1.2.1.31; EC 1.2.1.3; EC 1.2.1.8; EC 1.2.1; ALDH7A1 |
| Gene ID | 501 |
| UniProt ID | P49419 |
| Target Overview | The protein encoded by this gene is a member of subfamily 7 in the aldehyde dehydrogenase gene family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This particular member has homology to a previously described protein from the green garden pea, the 26g pea turgor protein. It is also involved in lysine catabolism that is known to occur in the mitochondrial matrix. Recent reports show that this protein is found both in the cytosol and the mitochondria, and the two forms likely arise from the use of alternative translation initiation sites. An additional variant encoding a different isoform has also been found for this gene. Mutations in this gene are associated with pyridoxine-dependent epilepsy. Several related pseudogenes have also been identified. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |