This is an aptamer development services to screening aptamers binds to the ALG2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ALG2 |
| Alternative Names | ALG2 Alpha-1,3/1,6-Mannosyltransferase; Asparagine-Linked Glycosylation 2 Homolog (Yeast, Alpha-1,3-Mannosyltransferase) ; GDP-Man:Man(1)GlcNAc(2)-PP-Dol Alpha-1,3-Mannosyltransferase; GDP-Man:Man(2)GlcNAc(2)-PP-Dol Alpha-1,6-Mannosyltransferase; GDP-Man:Man(1)GlcNAc(2)-PP-Dolichol Mannosyltransferase; Asparagine-Linked Glycosylation Protein 2 Homolog; Alpha-1,3/1,6-Mannosyltransferase ALG2; HALPG2; CDG1I; CDGIi; NET38; Asparagine-Linked Glycosylation 2, Alpha-1,3-Mannosyltransferase Homolog (S. Cerevisiae) ; Asparagine-Linked Glycosylation 2 Homolog (S. Cerevisiae, Alpha-1,3-Mannosyltransferase) ; Asparagine-Linked Glycosylation 2, Alpha-1,3-Mannosyltransferase Homolog; Alpha-1,3-Mannosyltransferase ALG2; Homolog Of Yeast ALG2; EC 2.4.1.132; EC 2.4.1.257; FLJ14511; EC 2.4.1; CMSTA; CMS14; ALG2 |
| Gene ID | 85365 |
| UniProt ID | Q9H553 |
| Target Overview | This gene encodes a member of the glycosyltransferase 1 family. The encoded protein acts as an alpha 1,3 mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have been associated with congenital disorder of glycosylation type Ih (CDG-Ii). Alternative splicing results in multiple transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |