Anti-ANAPC10 Aptamer SELEX Service(Cat#: CTApt-1168)

This is an aptamer development services to screening aptamers binds to the ANAPC10 with an affinity of 1nM~1μM.

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Summary
Specifications
Target Category Protein
Target ANAPC10
Alternative Names Anaphase Promoting Complex Subunit 10; APC10; Anaphase-Promoting Complex Subunit 10; Cyclosome Subunit 10; DOC1; DKFZP564L0562; ANAPC10
Gene ID 10393
UniProt ID Q9UM13
Target Overview ANAPC10 is a core subunit of the anaphase-promoting complex (APC), or cyclosome, a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836), the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al., 2001 [PubMed 11524682]).
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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