Anti-ANKRD17 Aptamer SELEX Service(Cat#: CTApt-1249)

This is an aptamer development services to screening aptamers binds to the ANKRD17 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target ANKRD17
Alternative Names Ankyrin Repeat Domain 17; GTAR; Serologically Defined Breast Cancer Antigen NY-BR-16; Ankyrin Repeat Domain-Containing Protein 17; Gene Trap Ankyrin Repeat Protein; NY-BR-16; KIAA0697; MASK2; FLJ22206; ANKRD17
Gene ID 26057
UniProt ID O75179
Target Overview The protein encoded by this gene belongs to the family of ankyrin repeat-containing proteins, and contains two distinct arrays of ankyrin repeats in its amino-terminal region, one with 15 ankyrin repeats, and the other with 10 ankyrin repeats. It also contains a nuclear export signal, nuclear localization signal, and a cyclin-binding RXL motif. Localization of this protein to the nucleus has been shown experimentally, and interactions between this protein and cyclin-dependent kinase 2 have been observed. It has been suggested that this protein plays a role in both DNA replication and in both anti-viral and anti-bacterial innate immune pathways. Alternative splicing results in multiple transcript variants encoding different isoforms.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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