This is an aptamer development services to screening aptamers binds to the ANKS1B with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ANKS1B |
| Alternative Names | Ankyrin Repeat And Sterile Alpha Motif Domain Containing 1B; AIDA-1; EB-1; Ankyrin Repeat And Sterile Alpha Motif Domain-Containing Protein 1B; Cajalin-2; ANKS2; Amyloid-Beta Precursor Protein Intracellular Domain Associated Protein 1; Amyloid-Beta Protein Intracellular Domain-Associated Protein 1; E2a-Pbx1-Associated Protein; E2A-PBX1-Associated Protein; Cajalin 2; ANKS1B; AIDA; EB1 |
| Gene ID | 56899 |
| UniProt ID | Q7Z6G8 |
| Target Overview | This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |