Anti-Anthrax Lethal Factor Aptamer(Cat#: CTMM-0125-JL16)

Name: Anti-Anthrax Lethal Factor Aptamer
SKU: CTMM-0125-JL16
Rating: 5 (1 reviews)

This product is a customized aptamer which binds to Anthrax Lethal Factor with an affinity of 1-50 nM.

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Specifications

Target Category	Bacteria
Target	Anthrax Lethal Factor
Alternative Names	Lethal Factor
Target Overview	The Bacillus anthracis bacterium's primary virulence factor is a toxin known as the lethal factor (LF). This secreted toxin is highly lethal to the host by disrupting signaling pathways, causing cell destruction, and inducing circulatory shock.
Type	DNA
Length	<50 nt
Affinity (Kd)	1-50 nM
Binding Conditions/Buffer	30 mM Tris-HCl, pH 8.4, 3.0 mM KCl, 600 mM NaCl, and 0.6 mM MgCl₂
GC Content	66.67%
Molecular Weight	9249.02 g/mole
nmoles/OD260	3.58038