This is an aptamer development services to screening aptamers binds to the AP2A1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | AP2A1 |
| Alternative Names | Adaptor Related Protein Complex 2 Subunit Alpha 1; Clathrin Assembly Protein Complex 2 Alpha-A Large Chain; Plasma Membrane Adaptor HA2/AP2 Adaptin Alpha A Subunit; Adaptor Related Protein Complex 2 Alpha 1 Subunit; Adaptor Protein Complex AP-2 Subunit Alpha-1; 100 KDa Coated Vesicle Protein A; AP-2 Complex Subunit Alpha-1; Alpha-Adaptin A; Alpha1-Adaptin; CLAPA1; ADTAA; Clathrin-Associated/Assembly/Adaptor Protein, Large, Alpha 1; Adapter-Related Protein Complex 2 Alpha-1 Subunit; Adapter-Related Protein Complex 2 Subunit Alpha-1; Adaptor-Related Protein Complex 2 Subunit Alpha-1; Adaptin, Alpha A; AP2-ALPHA; AP2A1 |
| Gene ID | 160 |
| UniProt ID | O95782 |
| Target Overview | This gene encodes the alpha 1 adaptin subunit of the adaptor protein 2 (AP-2) complex found in clathrin coated vesicles. The AP-2 complex is a heterotetramer consisting of two large adaptins (alpha or beta), a medium adaptin (mu), and a small adaptin (sigma). The complex is part of the protein coat on the cytoplasmic face of coated vesicles which links clathrin to receptors in vesicles. Alternative splicing of this gene results in two transcript variants encoding two different isoforms. A third transcript variant has been described, but its full length nature has not been determined. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |