Anti-APRT Aptamer SELEX Service(Cat#: CTApt-2138)

Name: Anti-APRT Aptamer SELEX Service
SKU: CTApt-2138
Rating: 5 (1 reviews)

This is an aptamer development services to screening aptamers binds to the APRT with an affinity of 1nM~1μM.

Certificate of Analysis Lookup

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Lot Number

Specifications

Target Category	Protein
Target	APRT
Alternative Names	Adenine Phosphoribosyltransferase; EC 2.4.2.7; Transphosphoribosidase; AMP Pyrophosphorylase; AMP Diphosphorylase; APRTD; APRT; AMP
Gene ID	353
UniProt ID	P07741
Target Overview	Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
Chemical Modification	N/A
Type	DNA
Length	20-80 nt
Affinity (Kd)	1nM~1μM
Binding Conditions/Buffer	PBS; buffer system with Serum; other