This is an aptamer development services to screening aptamers binds to the ARFGAP1 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ARFGAP1 |
| Alternative Names | ADP Ribosylation Factor GTPase Activating Protein; ADP-Ribosylation Factor GTPase-Activating Protein; ARF1-Directed GTPase-Activating Protein; ARF1GAP; ADP-Ribosylation Factor 1 GTPase Activating Protein; ADP-Ribosylation Factor 1 GTPase-Activating Protein; HRIHFB2281; BA261N11.3; ARF GAP; FLJ10767; ARF1 GAP; ARFGAP1 |
| Gene ID | 55738 |
| UniProt ID | Q8N6T3 |
| Target Overview | The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |