Anti-ARHGAP26 Aptamer SELEX Service(Cat#: CTApt-2531)

This is an aptamer development services to screening aptamers binds to the ARHGAP26 with an affinity of 1nM~1μM.

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Summary
Specifications
Target Category Protein
Target ARHGAP26
Alternative Names Rho GTPase Activating Protein 26; OPHN1L; GRAF; Rho GTPase-Activating Protein 26; Oligophrenin-1-Like Protein; KIAA0621; OPHN1L1; GTPase Regulator Associated With Focal Adhesion Kinase Pp125(FAK) ; GTPase Regulator Associated With The Focal Adhesion Kinase Pp125; GTPase Regulator Associated With Focal Adhesion Kinase; Rho-Type GTPase-Activating Protein 26; ARHGAP26; GRAF1
Gene ID 23092
UniProt ID Q9UNA1
Target Overview Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Multiple transcript variants encoding different isoforms have been found for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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