This is an aptamer development services to screening aptamers binds to the ATP2A3 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ATP2A3 |
| Alternative Names | ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 3; Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 3; Calcium Pump 3; SERCA3; ATPase, Ca++ Transporting, Ubiquitous; SR Ca(2+)-ATPase 3; Sarco/Endoplasmic Reticulum Ca2+ -ATPase; ATPase, Ca(2+)-Transporting, Ubiquitous; Calcium-Translocating P-Type ATPase; Adenosine Triphosphatase, Calcium; EC 7.2.2.10; EC 3.6.3.8; EC 3.6.3; ATP2A3 |
| Gene ID | 489 |
| UniProt ID | Q93084 |
| Target Overview | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |