This is an aptamer development services to screening aptamers binds to the ATP6V0B with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | ATP6V0B |
| Alternative Names | ATPase H+ Transporting V0 Subunit B; HATPL; ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit B; V-Type Proton ATPase 21 KDa Proteolipid Subunit; Vacuolar Proton Pump 21 KDa Proteolipid Subunit; V-ATPase 21 KDa Proteolipid Subunit; ATP6F; VMA16; ATPase, H+ Transporting, Lysosomal, 21-KD, V0 Subunit C-Prime, Prime; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump) 21kD; ATPase, H+ Transporting, Lysosomal 21kDa, V0 Subunit C''; Vacuolar ATP Synthase 21 KDa Proteolipid Subunit; H(+)-Transporting Two-Sector ATPase, Subunit F; ATPase, H+ Transporting, Lysosomal, Subunit F; V-ATPase Subunit C''; ATP6V0B |
| Gene ID | 533 |
| UniProt ID | Q99437 |
| Target Overview | This gene encodes a portion of the V0 domain of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. Activity of this enzyme is necessary for such varied processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. Alternative splicing results in multiple transcript variants. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |