Anti-ATP6V0C Aptamer SELEX Service(Cat#: CTApt-2283)
This is an aptamer development services to screening aptamers binds to the ATP6V0C with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
ATP6V0C |
| Alternative Names |
ATPase H+ Transporting V0 Subunit C; ATPase, H+ Transporting, Lysosomal 16kDa, V0 Subunit C; V-Type Proton ATPase 16 KDa Proteolipid Subunit; Vacuolar Proton Pump 16 KDa Proteolipid Subunit; V-ATPase 16 KDa Proteolipid Subunit; ATP6C; ATP6L; ATPL; VATL; Vma3; ATPase, H+ Transporting, Lysosomal (Vacuolar Proton Pump) 16kD; H(+)-Transporting Two-Sector ATPase, 16 KDa Subunit; Vacuolar ATP Synthase 16 KDa Proteolipid Subunit; Vacuolar H+ ATPase Proton Channel Subunit; ATP6V0C; VPPC |
| Gene ID |
527 |
| UniProt ID |
P27449 |
| Target Overview |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. This gene encodes the V0 subunit c. Alternative splicing results in transcript variants. Pseudogenes have been identified on chromosomes 6 and 17. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
