This is an aptamer development services to screening aptamers binds to the BCHE with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BCHE |
| Alternative Names | Butyrylcholinesterase; Acylcholine Acylhydrolase; Cholinesterase (Serum) 2; Butyrylcholine Esterase; Pseudocholinesterase; Choline Esterase II; Cholinesterase 1; Cholinesterase; EC 3.1.1.8; CHE1; E1; EC 3.1.1; BCHED; CHE2; BCHE |
| Gene ID | 590 |
| UniProt ID | P06276 |
| Target Overview | This gene encodes a cholinesterase enzyme and member of the type-B carboxylesterase/lipase family of proteins. The encoded enzyme exhibits broad substrate specificity and is involved in the detoxification of poisons including organophosphate nerve agents and pesticides, and the metabolism of drugs including cocaine, heroin and aspirin. Humans homozygous for certain mutations in this gene exhibit prolonged apnea after administration of the muscle relaxant succinylcholine. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |