Anti-BCL11B aptamer SELEX Service(Cat#: CTApt-1875)

This is an aptamer development services to screening aptamers binds to the BCL11B with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BCL11B
Alternative Names BAF Chromatin Remodeling Complex Subunit BCL11B; CTIP2; Radiation-Induced Tumor Suppressor Gene 1 Protein; B-Cell CLL/Lymphoma 11B (Zinc Finger Protein) ; BCL11B, BAF Complex Component; COUP-TF-Interacting Protein 2; B-Cell Lymphoma/Leukemia 11B; B Cell CLL/Lymphoma 11B; HRIT1-Alpha; BCL-11B; CTIP-2; HRit1; RIT1; B-Cell CLL/Lymphoma 11B/T-Cell Receptor Delta Constant Region Fusion Protein; Zinc Finger Protein HRit1 Alpha; B-Cell Lymphoma/Leukaemia 11B; B-Cell CLL/Lymphoma 11B; BCL11B/TRDC Fusion; ATL1-Alpha; ATL1-Delta; ATL1-Gamma; ATL1-Beta; IDDFSTA; ZNF856B; BCL11B; IMD49; ATL1
Gene ID 64919
UniProt ID Q9C0K0
Target Overview This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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