Anti-BCL2L10 aptamer SELEX Service(Cat#: CTApt-1878)

This is an aptamer development services to screening aptamers binds to the BCL2L10 with an affinity of 1nM~1μM.

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Summary
Specifications
Target Category Protein
Target BCL2L10
Alternative Names BCL2 Like 10; BCL2-Like 10 (Apoptosis Facilitator) ; Anti-Apoptotic Protein NrH; Apoptosis Regulator Bcl-B; Bcl-2-Like Protein 10; Bcl2-L-10; BCL-B; Diva; Boo; Death Inducer Binding To VBcl-2 And Apaf-1; BCL2L10; BCLB
Gene ID 10017
UniProt ID Q9HD36
Target Overview The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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