Anti-BCOR aptamer SELEX Service(Cat#: CTApt-1725)

This is an aptamer development services to screening aptamers binds to the BCOR with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BCOR
Alternative Names BCL6 Corepressor; BCL6 Interacting Corepressor; BCL-6 Corepressor; BCL-6 Coreceptor; KIAA1575; BCL-6 Interacting Corepressor; BCL6 Co-Repressor; FLJ20285; MCOPS2; ANOP2; MAA2; BCOR; BCoR
Gene ID 54880
UniProt ID Q6W2J9
Target Overview The protein encoded by this gene was identified as an interacting corepressor of BCL6, a POZ/zinc finger transcription repressor that is required for germinal center formation and may influence apoptosis. This protein selectively interacts with the POZ domain of BCL6, but not with eight other POZ proteins. Specific class I and II histone deacetylases (HDACs) have been shown to interact with this protein, which suggests a possible link between the two classes of HDACs. Several transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome Y.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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