This is an aptamer development services to screening aptamers binds to the BEST2 with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BEST2 |
| Alternative Names | Bestrophin 2; Vitelliform Macular Dystrophy 2-Like Protein 1; Vitelliform Macular Dystrophy 2-Like 1; Bestrophin-2; VMD2L1; VMD2-Like Gene 1; FLJ20132; BEST2 |
| Gene ID | 54831 |
| UniProt ID | Q8NFU1 |
| Target Overview | This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |