This is an aptamer development services to screening aptamers binds to the BMP8A with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BMP8A |
| Alternative Names | Bone Morphogenetic Protein 8a; Bone Morphogenetic Protein 8A; BMP-8A; OP-2; BMP8A |
| Gene ID | 353500 |
| UniProt ID | Q7Z5Y6 |
| Target Overview | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein may play a role in development of the reproductive system. This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |