Anti-BMPR2 aptamer SELEX Service(Cat#: CTApt-1770)
This is an aptamer development services to screening aptamers binds to the BMPR2 with an affinity of 1nM~1μM.
Specific Inquiry 
Specifications
| Target Category |
Protein |
| Target |
BMPR2 |
| Alternative Names |
Bone Morphogenetic Protein Receptor Type 2; Bone Morphogenetic Protein Receptor Type II; BMPR-II; Bone Morphogenetic Protein Receptor, Type II (Serine/Threonine Kinase) ; Bone Morphogenetic Protein Receptor Type-2; BMP Type II Receptor; BMP Type-2 Receptor; EC 2.7.11.30; BMPR3; BRK-3; T-ALK; PPH1; Type II Receptor For Bone Morphogenetic Protein-4; Type II Activin Receptor-Like Kinase; Primary Pulmonary Hypertension 1; EC 2.7.11; BMPR-2; POVD1; BMPR2; BMR2 |
| Gene ID |
659 |
| UniProt ID |
Q13873 |
| Target Overview |
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. |
| Chemical Modification |
N/A |
| Type |
DNA |
| Length |
20-80 nt |
| Affinity (Kd) |
1nM~1μM |
| Binding Conditions/Buffer |
PBS; buffer system with Serum; other |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
