This is an aptamer development services to screening aptamers binds to the BMX with an affinity of 1nM~1μM.
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| Target Category | Protein |
| Target | BMX |
| Alternative Names | BMX Non-Receptor Tyrosine Kinase; ETK; Bone Marrow Tyrosine Kinase Gene In Chromosome X Protein; Epithelial And Endothelial Tyrosine Kinase; Cytoplasmic Tyrosine-Protein Kinase BMX; BTK-Like On X Chromosome; EC 2.7.10.2; PSCTK3; Etk/Bmx Cytosolic Tyrosine Kinase; NTK38 Tyrosine Kinase; EC 2.7.10; PSCTK2; NTK38; BMX |
| Gene ID | 660 |
| UniProt ID | P51813 |
| Target Overview | This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Alternatively spliced transcript variants have been found for this gene. |
| Chemical Modification | N/A |
| Type | DNA |
| Length | 20-80 nt |
| Affinity (Kd) | 1nM~1μM |
| Binding Conditions/Buffer | PBS; buffer system with Serum; other |