This product is a customized aptamer which binds to Botulinum Neurotoxin E with an affinity of 50-200 nM.
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| Target Category | Small Molecule |
| Target | Botulinum Neurotoxin E |
| Alternative Names | BoNT type E toxoid; BoNTE |
| Target Overview | Botulinum neurotoxin E (BoNT/E) is one of the seven serotypes within the Botulinum Neurotoxins (BoNTs) family, which are produced by diverse strains of Clostridium botulinum. It stands as a prominent cause of human botulism yet paradoxically holds promise as a therapeutic agent. |
| Type | DNA |
| Length | <50 nt |
| Affinity (Kd) | 50-200 nM |
| Binding Conditions/Buffer | 25 mM Tris-HCl, pH 8.0, 100 mM NaCl, 25 mM KCl, 10 mM MgCl₂ |
| GC Content | 0.4872 |
| Molecular Weight | 12099.92 g/mole |
| nmoles/OD260 | 2.70416 |