Anti-BTNL2 aptamer SELEX Service(Cat#: CTApt-1874)

This is an aptamer development services to screening aptamers binds to the BTNL2 with an affinity of 1nM~1μM.

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Summary

Specifications
Target Category Protein
Target BTNL2
Alternative Names Butyrophilin Like 2; BTL-II; Butyrophilin-Like 2 (MHC Class II Associated) ; Butyrophilin-Like Protein 2; HSBLMHC1; BTN7; Butyrophilin-Like 2; Truncated BTNL2; BTNL2; SS2
Gene ID 56244
UniProt ID Q9UIR0
Target Overview This gene encodes a major histocompatibility complex, class II associated, type I transmembrane protein which belongs to the butyrophilin-like B7 family of immunoregulators. It is thought to be involved in immune surveillance, serving as a negative T-cell regulator by decreasing T-cell proliferation and cytokine release. The encoded protein contains an N-terminal signal peptide, two pairs of immunoglobulin-like domains, separated by a heptad peptide sequence, and a C-terminal transmembrane domain. Naturally occurring mutations in this gene are associated with sarcoidosis, rheumatoid arthritis, ulcerative colitis, inflammatory bowel disease, myositis, type 1 diabetes, systemic lupus erythematosus, acute coronary syndrome, and prostate cancer.
Chemical Modification N/A
Type DNA
Length 20-80 nt
Affinity (Kd) 1nM~1μM
Binding Conditions/Buffer PBS; buffer system with Serum; other
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
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