Anti-α-Bungarotoxin Aptamer(Cat#: CTMM-0624-LH9)
This product is a customized aptamer which binds to α-Bungarotoxin with an affinity of 1-50 μM.
Specific Inquiry 
Specifications
| Target Category |
Toxin |
| Target |
α-Bungarotoxin |
| Target Overview |
α-Bungarotoxin is one of the bungarotoxins, components of the venom of the elapid Taiwanese banded krait snake (Bungarus multicinctus). It is a type of α-neurotoxin, a neurotoxic protein that is known to bind competitively and in a relatively irreversible manner to the nicotinic acetylcholine receptor found at the neuromuscular junction, causing paralysis, respiratory failure, and death in the victim. It has also been shown to play an antagonistic role in the binding of the α7 nicotinic acetylcholine receptor in the brain, and as such has numerous applications in neuroscience research. |
| Type |
RNA |
| Length |
50-100 nt |
| Affinity (Kd) |
1-50 μM |
| Binding Conditions/Buffer |
137 mM NaCl, 2.7 mM KCl, 4.2 mM Na₂HPO₄, 1.47 mM KH₂PO₄, 0.005% Tween 20 |
| GC Content |
59% |
| Molecular Weight |
26639 g/mole |
| nmoles/OD260 |
1.031 |
For Research Use Only. Not for Diagnostic or Therapeutic Applications.
